isni: Index of Local Sensitivity to Nonignorability

The current version provides functions to compute, print and summarize the Index of Sensitivity to Nonignorability (ISNI) in the generalized linear model for independent data, and in the marginal multivariate Gaussian model and the mixed-effects models for continuous and binary longitudinal/clustered data. It allows for arbitrary patterns of missingness in the regression outcomes caused by dropout and/or intermittent missingness. One can compute the sensitivity index without estimating any nonignorable models or positing specific magnitude of nonignorability. Thus ISNI provides a simple quantitative assessment of how robust the standard estimates assuming missing at random is with respect to the assumption of ignorability. For a tutorial, download at <>. For more details, see Troxel Ma and Heitjan (2004) and Xie and Heitjan (2004) <doi:10.1191/1740774504cn005oa> and Ma Troxel and Heitjan (2005) <doi:10.1002/sim.2107> and Xie (2008) <doi:10.1002/sim.3117> and Xie (2012) <doi:10.1016/j.csda.2010.11.021> and Xie and Qian (2012) <doi:10.1002/jae.1157>.

Version: 1.3
Depends: R (≥ 3.0.1)
Imports: nlme, mvtnorm, nnet, matrixcalc, Formula, lme4
Suggests: knitr, rmarkdown
Published: 2021-08-23
DOI: 10.32614/CRAN.package.isni
Author: Hui Xie, Weihua Gao, Baodong Xing, Daniel Heitjan, Donald Hedeker, Chengbo Yuan
Maintainer: Hui Xie <huixie at>
License: GPL-2
NeedsCompilation: no
Citation: isni citation info
Materials: NEWS
In views: MissingData
CRAN checks: isni results


Reference manual: isni.pdf
Vignettes: ISNI


Package source: isni_1.3.tar.gz
Windows binaries: r-devel:, r-release:, r-oldrel:
macOS binaries: r-release (arm64): isni_1.3.tgz, r-oldrel (arm64): isni_1.3.tgz, r-release (x86_64): isni_1.3.tgz, r-oldrel (x86_64): isni_1.3.tgz
Old sources: isni archive


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