HCTDesign: Group Sequential Design for Historical Control Trial with Survival Outcome

It provides functions to design historical controlled trials with survival outcome by group sequential method. The options for interim look boundaries are efficacy only, efficacy & futility or futility only. It also provides the function to monitor the trial for any unplanned look. The package is based on Jianrong Wu, Xiaoping Xiong (2016) <doi:10.1002/pst.1756> and Jianrong Wu, Yimei Li (2020) <doi:10.1080/10543406.2019.1684305>.

Version: 0.7.1
Imports: Rdpack, diversitree, mvtnorm, flexsurv, stats, survival
Published: 2022-03-10
Author: Tushar Patni [aut, cre], Yimei Li [aut], Jianrong Wu [aut], Arzu Onar-Thomas [aut]
Maintainer: Tushar Patni <patni006 at umn.edu>
License: GPL-3
NeedsCompilation: no
CRAN checks: HCTDesign results


Reference manual: HCTDesign.pdf


Package source: HCTDesign_0.7.1.tar.gz
Windows binaries: r-devel: HCTDesign_0.7.1.zip, r-release: HCTDesign_0.7.1.zip, r-oldrel: HCTDesign_0.7.1.zip
macOS binaries: r-release (arm64): HCTDesign_0.7.1.tgz, r-oldrel (arm64): HCTDesign_0.7.1.tgz, r-release (x86_64): HCTDesign_0.7.1.tgz, r-oldrel (x86_64): HCTDesign_0.7.1.tgz
Old sources: HCTDesign archive


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