PO.EN: An Elastic-Net Regularized Presence-Only Model

Presence-only model with Elastic Net penalty is a regularized generalized linear model training on the presence-absence response. This package provides functions for tuning and fitting the presence-only model. The presence-only model can be used to predict regulatory effects of genetic variants at sequence-level resolution by integrating a large number of epigenetic features and massively parallel reporter assays (MPRAs).

Version: 1.0
Depends: R (≥ 3.1.0)
Imports: Rcpp, PUlasso, glmnet, pROC
LinkingTo: Rcpp, RcppArmadillo
Published: 2020-08-19
Author: Zikun Yang [aut, cre, cph], Chen Wang [ctb], Iuliana Ionita-Laza [aut, ctb]
Maintainer: Zikun Yang <yangzikun1125 at gmail.com>
License: GPL-2 | GPL-3 [expanded from: GPL (≥ 2)]
NeedsCompilation: yes
CRAN checks: PO.EN results


Reference manual: PO.EN.pdf
Package source: PO.EN_1.0.tar.gz
Windows binaries: r-devel: PO.EN_1.0.zip, r-devel-UCRT: PO.EN_1.0.zip, r-release: PO.EN_1.0.zip, r-oldrel: PO.EN_1.0.zip
macOS binaries: r-release: PO.EN_1.0.tgz, r-oldrel: PO.EN_1.0.tgz


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